Open science.
Closed hype.

Data, methods, and validation pipelines are open unless there is a compelling reason to restrict. Science advances through transparency.

🔬 "If evidence changes, our models change. Truth is versioned."

A living system that
continuously learns.

Every outcome becomes new evidence. Every decision feeds back into the system. This is not a pipeline — it is a cycle.

EQAI Living
Infrastructure
👁
Observation
📊
Evidence
Validation
🧠
Knowledge
Foundation
Intelligence
🎯
Prediction
📋
Decision
📈
Outcome

Raw ObservationEvidenceValidationKnowledgeFoundation IntelligencePredictionDecisionOutcomeNew Observation

Every JumpHealth™, JumpID™, and JumpChain™ report generates new evidence that feeds back into the system.

Five layers of
rigorous validation.

Every EQAI finding passes through multiple validation stages before it reaches users. Nothing is published without traceable evidence.

1

Internal Validation

Coordinate consistency checks, allele frequency validation, Hardy-Weinberg equilibrium testing across all genotype data.

✅ Achieved
2

Cross-Breed Validation

Findings verified across independent breed populations. Associations must replicate in multiple genetic backgrounds.

✅ Achieved
3

Literature Validation

Every variant cross-referenced with dbSNP rsID, OMIA disease associations, and peer-reviewed publications.

✅ Achieved
4

Expert Review

Domain expert review of interpretations. Veterinary geneticists validate clinical relevance of findings.

🔄 In Progress
5

Continuous Re-validation

Ongoing validation as new data arrives. Conclusions are versioned and updated when evidence changes.

🔄 In Progress

Validated research.
Open results.

❄️

Cold Adaptation Study

Systematic investigation into genetic basis of cold tolerance across 17 equine breeds. Candidate gene identification with cross-breed validation.

57 Candidates
14 Tier A
43 Tier B
✅ Validated
🧬

NCDS Gene Model v3.4

Neural-Cognitive-Developmental System — a three-layer hierarchical model for complex equine traits organization.

102 Genes
3 Layers
✅ v3.4 Complete
🐎

Breed Frequency Database

Comprehensive allele frequency database across equine breeds — foundation for breed-specific risk assessment.

17 Breeds
9 Production
🔄 Expanding

Open by default.
FAIR by design.

F

Findable

Standard identifiers and searchable indices

A

Accessible

Versioned releases via open APIs

I

Interoperable

Standard schemas for integration

R

Reusable

Clear provenance and licensing

If evidence changes,
our models change.
Truth is versioned.

Every EQAI output includes a version number, a data source timestamp, and a validation status. When new evidence contradicts an existing conclusion, the conclusion is updated — and the change is published. Missing evidence is surfaced, not hidden.